When I was fifteen I went for a psychiatric evaluation at the local hospital’s out-patient facility. I don’t remember how I got the referral, I suspect my Mum got one through our local GP. There were all kinds of people in the waiting room; some were clearly very distressed or catatonic, some had severe intellectual handicaps, and all of them sitting in various states of agitation. Welcoming was not a word I would use to describe this space. After the evaluation, I remember Mum telling me how alarmed she felt to bring me there and how I just didn’t seem to fit among that group of people. If only all mental illnesses were so equally obvious, talk about starting at a disadvantage.
An article just published online in the latest issue of Nature indicates that a metabolite of (R, S)-ketamine, rather that the drug itself, is the responsible agent for it’s fast-acting anti-depressant effect.